COLUMBUS, Ohio – Scientists at The Ohio State University College of Medicine have discovered that cells in the spinal cord that prevent regeneration after a spinal cord injury (SCI) can be manipulated, through gene therapy, to become increasingly supportive of repair.
The study, published yesterday (18 Oct) in the Journal of Neuroscience, shows that treating an injured adult spinal cord, by genetic delivery of a high-level growth factor found in the developing brain, can change the behavior of glial scar cells called astrocytes.